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5,53 While numbers of the current drugs in clinical trials generally achieved the effect of improving NASH histopathology (hepatic steatosis, etc.) or without worsening fibrosis, future studies are needed to translate into appropriate clinical applications

Adhesion complex regulators When integrins bind to ECM proteins, the involvement of large protein complexes and signal transduction occur leading to the formation of various evolving complexes, such as primitive adhesions, focal complexes, FAs and fibrillar adhesions [83]

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